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Hydroxyl radicals and DNA base damage

Jean Cadet, Thierry Delatour, Thierry Douki, Didier Gasparutto, Jean-Pierre Pouget, Jean-Luc Ravanat, Sylvie Sauvaigo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1999

Langue:

english

Fichier:

PDF, 212 KB

english, 1999

436 A new global anti-aging cosmetic active ingredient with specific activity on neuro-aging, dermal matrix and DNA repair to provide protection against chronological and actinic skin aging

Bredif, S., Martin, M., Leclere-Bienfait, S., Moulinet, C., Gras-Lavigne, E., Sauvaigo, S., Baudouin, C.

Journal:

The Journal of Investigative Dermatology

Année:

2016

Langue:

english

Fichier:

PDF, 53 KB

english, 2016

Analysis of Fluoroquinolone-mediated Photosensitization of 2′-Deoxyguanosine, Calf Thymus and Cellular DNA: Determination of Type-I, Type-II and Triplet–Triplet Energy Transfer Mechanism Contribution

Sylvie Sauvaigo, Thierry Douki, Francette Odin, Sylvain Caillat, Jean-Luc Ravanat, Jean Cadet

Journal:

Photochemistry and Photobiology

Année:

2001

Langue:

english

Fichier:

PDF, 133 KB

english, 2001

TiO2 nanoparticles exhibit genotoxicity and impair both NER and BER DNA repair pathways in A549 cells

M. Carrière, M. Jugan, S. Barillet, A. Simon-Deckers, S. Sauvaigo, T. Douki, N. Herlin-Boime

Journal:

Toxicology Letters

Année:

2011

Langue:

english

Fichier:

PDF, 60 KB

english, 2011

Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses

Carriere, Marie, Sauvaigo, Sylvie, Douki, Thierry, Ravanat, Jean-Luc

Journal:

Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 642 KB

english, 2016

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

Biola-Clier, M., Beal, D., Caillat, S., Libert, S., Armand, L., Herlin-Boime, N., Sauvaigo, S., Douki, T., Carriere, M.

Journal:

Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2016

New Synthesis of 5-Carboxy-2′-deoxyuridine and Its Incorporation into Synthetic Oligonucleotides

V. Guerniou, D. Gasparutto, S. Sauvaigo, A. Favier, J. Cadet

Journal:

ChemInform

Année:

2004

Fichier:

PDF, 53 KB

2004

Autonomous proliferation of mewo human melanoma cell lines in serum-free medium: Secretion of growth-stimulating activities

Sylvie Sauvaigo, Ruth E. Fretts, Richard J. Riopelle, Alain E. Lagarde

Journal:

International Journal of Cancer

Année:

1986

Langue:

english

Fichier:

PDF, 1.04 MB

english, 1986

Use of the Single-Cell Gel Electrophoresis Assay for the Immunofluorescent Detection of Specific DNA Damage

Sylvie Sauvaigo, Christine Serres, Nathalie Signorini, Nathalie Emonet, Marie-Jeanne Richard, Jean Cadet

Journal:

Analytical Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 208 KB

english, 1998

Comet Assay Coupled to Repair Enzymes for the Detection of Oxidative Damage to DNA Induced by Low Doses of γ-Radiation: Use of YOYO-1, Low-Background Slides, and Optimized Electrophoresis Conditions

Sylvie Sauvaigo, Crina Petec-Calin, Sylvain Caillat, Francette Odin, Jean Cadet

Journal:

Analytical Biochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 46 KB

english, 2002

Ageing effects on the expression of cell defence genes after UVA irradiation in human male cutaneous fibroblasts using cDNA arrays

Florence Hazane, Kita Valenti, Sylvie Sauvaigo, André Peinnequin, Catherine Mouret, Alain Favier, Jean-Claude Beani

Journal:

Journal of Photochemistry and Photobiology B: Biology

Année:

2005

Langue:

english

Fichier:

PDF, 223 KB

english, 2005

Age-dependent DNA repair and cell cycle distribution of human skin fibroblasts in response to UVA irradiation

Florence Hazane, Sylvie Sauvaigo, Thierry Douki, Alain Favier, Jean-Claude Beani

Journal:

Journal of Photochemistry and Photobiology B: Biology

Année:

2006

Langue:

english

Fichier:

PDF, 190 KB

english, 2006

Synthesis and enzymatic incorporation of morpholino thymidine-5′-triphosphate in DNA fragments

Florence Marciacq, Sylvie Sauvaigo, Jean-Paul Issartel, Jean-François Mouret, Didier Molko

Journal:

Tetrahedron Letters

Année:

1999

Langue:

english

Fichier:

PDF, 257 KB

english, 1999

An oligonucleotide microarray for the monitoring of repair enzyme activity toward different DNA base damage

Sylvie Sauvaigo, Valérie Guerniou, Delphine Rapin, Didier Gasparutto, Sylvain Caillat, Alain Favier

Journal:

Analytical Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2004

E6* oncoprotein expression of human papillomavirus type-16 determines different ultraviolet sensitivity related to glutathione and glutathione peroxidase antioxidant defence

Stéphane Mouret, Sylvie Sauvaigo, André Peinnequin, Alain Favier, Jean-Claude Beani, Marie-Thérèse Leccia

Journal:

Experimental Dermatology

Année:

2005

Langue:

english

Fichier:

PDF, 171 KB

english, 2005

DNA repair capacities of cutaneous fibroblasts: effect of sun exposure, age and smoking on response to an acute oxidative stress

S. Sauvaigo, M. Bonnet-Duquennoy, F. Odin, F. Hazane-Puch, N. Lachmann, F. Bonté, R. Kurfürst, A. Favier

Journal:

British Journal of Dermatology

Année:

2007

Langue:

english

Fichier:

PDF, 547 KB

english, 2007

Sensitivity to oxidative damage and DNA repair capacity of Japanese skin

S. Sauvaigo, M. Bonnet-Duquennoy, F. Odin, F. Hazane, R. Kurfürst, A. Favier

Journal:

International Journal of Cosmetic Science

Année:

2005

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2005

Unrepaired Cyclobutane Pyrimidine Dimers Do Not Prevent Proliferation of UV-B-irradiated Cultured Human Fibroblasts

Sophie Courdavault, Caroline Baudouin, Sylvie Sauvaigo, Stéphane Mouret, Serge Candéias, Marie Charveron, Alain Favier, Jean Cadet, Thierry Douki

Journal:

Photochemistry and Photobiology

Année:

2004

Langue:

english

Fichier:

PDF, 880 KB

english, 2004

The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: Its redox biomarkers

Yves Nzengue, Serge M. Candéias, Sylvie Sauvaigo, Thierry Douki, Alain Favier, Walid Rachidi, Pascale Guiraud

Journal:

Journal of Trace Elements in Medicine and Biology

Année:

2011

Langue:

english

Fichier:

PDF, 613 KB

english, 2011

Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts

Bénédicte Pons, Anne-Sophie Belmont, Gwénaëlle Masson-Genteuil, Violaine Chapuis, Thierry Oddos, Sylvie Sauvaigo

Journal:

Mechanisms of Ageing and Development

Année:

2010

Langue:

english

Fichier:

PDF, 286 KB

english, 2010

Direct inhibition of excision/synthesis DNA repair activities by cadmium: Analysis on dedicated biochips

S. Candéias, B. Pons, M. Viau, S. Caillat, S. Sauvaigo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 484 KB

english, 2010

P XIV B.25 - P XIV B.25 Immunofluorescent detection of cyclobutane pyrimidine dimers by a modification of the comet assay

Sylvie Sauvaigo, Nathalie Signorini, Nathalie Emonet, Marie-Jeanne Richard, Jean Cadet

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 136 KB

english, 1997

O XVI A.4 - O XVI A.4 Measurement of oxidative base damage within cellular DNA and biological fluids

Jean Cadet, Thierry Douki, Didier Molko, Jean-Luc Ravanat, Sylvie Sauvaigo, Nathalie Signorini, Zorana Tuce

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

1997

Langue:

english

Fichier:

PDF, 131 KB

english, 1997

Radiation-induced damage to DNA: mechanistic aspects and measurement of base lesions

J Cadet, T Douki, D Gasparutto, M Gromova, J.-P Pouget, J.-L Ravanat, A Romieu, S Sauvaigo

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Année:

1999

Langue:

english

Fichier:

PDF, 108 KB

english, 1999

Assessment of oxidative base damage to isolated and cellular DNA by HPLC-MS/MS measurement

Jean Cadet, Thierry Douki, Sandrine Frelon, Sylvie Sauvaigo, Jean-Pierre Pouget, Jean-Luc Ravanat

Journal:

Free Radical Biology and Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 140 KB

english, 2002

TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs

Christophe Bounaix Morand du Puch, Ewa Barbier, Alexandra Kraut, Yohann Couté, Julia Fuchs, Arnaud Buhot, Thierry Livache, Michel Sève, Alain Favier, Thierry Douki, Didier Gasparutto, Sylvie Sauvaigo,

Journal:

Archives of Biochemistry and Biophysics

Année:

2011

Langue:

english

Fichier:

PDF, 496 KB

english, 2011

Repair of oxidative damage of thymine by HeLa whole-cell extracts: simultaneous analysis using a microsupport and comparison with traditional PAGE analysis

Valérie Guerniou, Delphine Rapin, Jean-François Millau, Emmanuel Bufflier, Alain Favier, Jean Cadet, Sylvie Sauvaigo

Journal:

Biochimie

Année:

2005

Langue:

english

Fichier:

PDF, 406 KB

english, 2005

Enhancement of the in vitro transcription by T7 RNA polymerase of short DNA templates containing oxidative thymine lesions

Valérie Guerniou, Didier Gasparutto, Thierry Douki, Jean Cadet, Sylvie Sauvaigo

Journal:

Comptes Rendus Biologies

Année:

2005

Langue:

english

Fichier:

PDF, 485 KB

english, 2005

Assessment of DNA damage by comet assay on frozen total blood: method and evaluation in smokers and non-smokers

Isabelle Hininger, Alexia Chollat-Namy, Sylvie Sauvaigo, Mireille Osman, H Faure, Jean Cadet, Alain Favier, Anne-Marie Roussel

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2004

Langue:

english

Fichier:

PDF, 92 KB

english, 2004

Aging and photo-aging DNA repair phenotype of skin cells—Evidence toward an effect of chronic sun-exposure

Chloé Prunier, Gwénaëlle Masson-Genteuil, Nicolas Ugolin, Fanny Sarrazy, Sylvie Sauvaigo

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2012

Langue:

english

Fichier:

PDF, 866 KB

english, 2012

Identification of an amiloride sensitive Na+/H+ exchange system in brain synaptosomes

Sylvie Sauvaigo, Paul Vigne, Christian Frelin, Michel Lazdunski

Journal:

Brain Research

Année:

1984

Langue:

english

Fichier:

PDF, 305 KB

english, 1984

Fast solid support detection of human papillomavirus in in vitro amplified DNA using a DNP-anti DNP monoclonal antibody couple

M. Baccard-Longère, B. Alpha-Bazin, C. Chypre, S. Sauvaigo, R. Téoule, P. Bernard, J.-M. Seigneurin

Journal:

Journal of Virological Methods

Année:

1994

Langue:

english

Fichier:

PDF, 680 KB

english, 1994

200 Response of cancer cell lines to chemotherapeutic drugs: DNA repair phenotyping as an early cell- and drug-specific exposure marker

S. Sauvaigo, J. Guy, S. Caillat

Journal:

European Journal of Cancer Supplements

Année:

2010

Langue:

english

Fichier:

PDF, 47 KB

english, 2010

New Synthesis of 5-Carboxy-2′-deoxyuridine and Its Incorporation into Synthetic Oligonucleotides

Guerniou, V., Gasparutto, D., Sauvaigo, S., Favier, A., Cadet, J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2003

Langue:

english

Fichier:

PDF, 180 KB

english, 2003

Cytotoxic and Genotoxic Impact of TiO2 Nanoparticles on A549 Cells

Jugan, M. L., Barillet, S., Simon-Deckers, A., Sauvaigo, S., Douki, T., Herlin, N., Carrière, M.

Journal:

Journal of Biomedical Nanotechnology

Année:

2011

Langue:

english

Fichier:

PDF, 3.82 MB

english, 2011

Tools and strategies for DNA damage interactome analysis

du Puch, Christophe Bounaix Morand, Barbier, Ewa, Sauvaigo, Sylvie, Gasparutto, Didier, Breton, Jean

Journal:

Mutation Research/Reviews in Mutation Research

Année:

2013

Langue:

english

Fichier:

PDF, 948 KB

english, 2013

1115 Impact of Radiotherapy on PBMCs DNa Repair Capacity – Use of a Multiplexed Functional Repair Assay

Sauvaigo, S., Sarrazy, F., Breton, J., Caillat, S., Chapuis, V.

Journal:

European Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 52 KB

english, 2012

Lack of HIV tat-gene amplification in blood monocytes compared to T lymphocytes

Innocenti, P, Sauvaigo, S, Téoule, R, Seigneurin, J.-M

Journal:

Research in Virology

Année:

1991

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1991

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

Jugan, Mary-Line, Barillet, Sabrina, Simon-Deckers, Angelique, Herlin-Boime, Nathalie, Sauvaigo, Sylvie, Douki, Thierry, Carriere, Marie

Journal:

Nanotoxicology

Année:

2012

Langue:

english

Fichier:

PDF, 672 KB

english, 2012

Radiation-mediated formation of complex damage to DNA: a chemical aspect overview

Ravanat, J-L, Breton, J, Douki, T, Gasparutto, D, Grand, A, Rachidi, W, Sauvaigo, S

Journal:

British Journal of Radiology

Année:

2014

Langue:

english

Fichier:

PDF, 570 KB

english, 2014

A microarray to measure repair of damaged plasmids by cell lysates

Millau, J.-F., Raffin, A.-L., Caillat, S., Claudet, C., Arras, G., Ugolin, N., Douki, T., Ravanat, J.-L., Breton, J., Oddos, T., Dumontet, C., Sarasin, A., Chevillard, S., Favier, A., Sauvaigo, S.

Journal:

Lab on a Chip

Année:

2008

Langue:

english

Fichier:

PDF, 545 KB

english, 2008

Facts and artifacts in the measurement of oxidative base damage to DNA

Cadet, Jean, D'Ham, Cedric, Douki, Thierry, Pouget, Jean-Pierre, Ravanat, Jean-Luc, Sauvaigo, Sylvie

Journal:

Free Radical Research

Année:

1998

Langue:

english

Fichier:

PDF, 883 KB

english, 1998

Nucleic Acids Probes in Diagnostic

Teoule, Robert, Bazins, Hervé, Fouqué, Brigitte, Roget, André, Sauvaigo, Sylvie

Journal:

Nucleosides and Nucleotides

Année:

1991

Langue:

english

Fichier:

PDF, 541 KB

english, 1991

Reinvestigation of 4-Thiothymidine-5′-triphosphate Synthesis

Bazin, H., Sauvaigo, S.

Journal:

Nucleosides and Nucleotides

Année:

1999

Langue:

english

Fichier:

PDF, 116 KB

english, 1999

Europium Cryptate Labeled Deoxyuridine-Triphosphate Analog: Synthesis and Enzymatic Incorporation

Alpha-bazin, B., Bazin, H., Guillemer, S., Sauvaigo, S., Mathis, G.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2000

Langue:

english

Fichier:

PDF, 601 KB

english, 2000

Singlet oxygen-mediated damage to cellular DNA determined by the comet assay associated with DNA repair enzymes

Ravanat, J.-L., Sauvaigo, S., Caillat, S., Martinez, G. R., Medeiros, M. H. G., Mascio, P. Di, Favier, A., Cadet, J.

Journal:

Biological Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 109 KB

english, 2004

Fast solid support detection of PCR amplified viral DNA sequences using radioiodinated or hapten labelled primers

Sauvaigo, S., Fouquè, B., Roget, A., Livache, T., Bazin, H., Chypre, C., Tèoule, R.

Journal:

Nucleic Acids Research

Année:

1990

Langue:

english

Fichier:

PDF, 2.51 MB

english, 1990

Enhanced Sensitivity of the RET Proto-Oncogene to Ionizing Radiation In vitro

Volpato, C. B., Martinez-Alfaro, M., Corvi, R., Gabus, C., Sauvaigo, S., Ferrari, P., Bonora, E., De Grandi, A., Romeo, G.

Journal:

Cancer Research

Année:

2008

Langue:

english

Fichier:

PDF, 267 KB

english, 2008

Solid support quantitation of c-myc PCR products using a cleavable reporter

Rhoer-Moja, Sandrine, Bazin, Hervé, Sauvaigo, Sylvie, Chypre, Camille, Vindimian, Monique

Journal:

Nucleic Acids Research

Année:

1994

Langue:

english

Fichier:

PDF, 183 KB

english, 1994

108: Response of cancer cell lines to chemotherapeutic drugs: DNA repair versus toxicity as an early exposure marker

Sylvie, Sauvaigo, Guy, Julie, Caillat, Sylvain

Journal:

Bulletin du Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 46 KB

english, 2010